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Time of day differences in the number of cytokine-immunoreactive cells in the rat visual and somatosensory cortices: test for activity dependence of cytokine proteins
Sleep is posited to be dependent upon wake activity that in turn increases activity-dependent sleep regulatory substances, such as nerve growth factor (NGF) and the cytokine, tumor necrosis factor alpha (TNFa or TNF). TNFa ...
Whisker stimulation increases the number of tumor necrosis factor Î±- immunoreactive cells in the primary somatosensory cortex
Tumor necrosis factor alpha (TNFa) is a cytokine that plays an important role in neural plasticity as well as in the regulation of sleep. Immunohistochemistry was used to locate and analyze TNFa- and Fos-immunoreactive ...