Now showing items 1-5 of 5
EFFECT OF IRON-NITROGEN COORDINATION (TYPE II BINDING) ON DRUG METABOLISM BY CYTOCHROME P450: STUDIES TO UNDERSTAND THE KINETICS, METABOLIC STABILITY AND REGIOSELECTIVITY
Cytochrome P450 (CYP) enzymes metabolize more than 80% of clinically used drugs. Given a large role of CYP enzymes in drug metabolism, one of the goals in pharmaceutical industry is to understand metabolic rate and ...
SYNTHESIS AND CHARACTERIZATION OF NOVEL NITROGEN-CONTAINING LIGANDS FOR METAL ION SEPARATIONS
A serious limiting factor in the continued development of nuclear power is the disposal of high-level radioactive waste from spent nuclear fuel. The PUREX process can be used for the recovery of U and Pu, but it does not ...
PENTAVALENT ACTINYL CATION-CATION COMPLEXES IN AQUEOUS AND NON-AQUEOUS MEDIA
A primary component of advanced nuclear fuel cycles is the separation of trivalent lanthanides from trivalent minor actinides. Due to similar chemistries of these two groups this separation is a challenging task. Redox-based ...
Understanding and utilizing DOTA coordination chemistry for trivalent lanthanide/actinide separation
This study reports the results of an investigation centered on increasing the understanding of the coordination chemistry of the tetraaza macrocyclic ligand 1,4,7,10-tetraazacyclododecane-N,N',N",N'"-tetraacetic (DOTA) ...
Novel Instrumental Approaches to Ion Mobility Spectrometry: Voltage-Sweep, High-Pressure, and Radiative-Ion-Ion-Recombination
Ion Mobility Spectrometry (IMS) provides reliable and fast detection in a multitude of worldwide environments. Many IMS systems are used in security applications where IMS's ability to rapidly detect explosives and narcotics ...