The Migraine Attack: Pathophysiology and Genetics
Weber, Ann M.
MetadataShow full item record
Despite a decade of progress, migraine headache remains prevalent, disabling, often undiagnosed, and undertreated. Migraines affect approximately 24% of the population, with 6% being men and approximately 18% being women. Analgesic overuse, insomnia, depression, and anxiety are often comorbid with migraine headaches, leading to an annual cost of labor lost and disability of $50 billion. Research has demonstrated a connection between genetic influence with neuronal and vascular imbalances in the central nervous system, leading to the emergence of the condition. This new knowledge, may one day, help in treating this chronic condition. Current treatment options include abortive and preventative therapies. The goal of therapy is to reduce frequency and severity of attacks, limiting the impact of migraine on activities of daily living.