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Identification of Anaplasma marginale type IV secretion system effector proteins
(PLoS ONE, 2011-11)
Anaplasma marginale, an obligate intracellular alphaproteobacterium in the order Rickettsiales, is a tick-borne pathogen and the leading cause of anaplasmosis in cattle worldwide. Complete genome sequencing of A. marginale ...
Comparative genomics reveals multiple pathways to mutualism for tick-borne pathogens
(BMC Genomics, 2016)
Background: Multiple important human and livestock pathogens employ ticks as their primary host vectors. It is not currently known whether this means of infecting a host arose once or many times during evolution. Results: ...
Whole proteome clustering of 2,307 Proteobacterial genomes reveals conserved proteins and significant annotation issues
(Frontiers in Microbiology, 2019)
We clustered 8.76 M protein sequences deduced from 2,307 completely sequenced Proteobacterial genomes resulting in 707,311 clusters of one or more sequences of which 224,442 ranged in size from 2 to 2,894 sequences. To our ...