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Primary structural variation in Anaplasma marginale Msp2 efficiently generates immune escape variants
(Infection and Immunity, 2015-11)
Antigenic variation allows microbial pathogens to evade immune clearance and establish persistent infection. Anaplasma marginale utilizes gene conversion of a repertoire of silent msp2 alleles into a single active expression ...
Automated training for algorithms that learn from genomic data
(BioMed Research International, 2015-01)
Supervised machine learning algorithms are used by life scientists for a variety of objectives. Expert-curated public gene and protein databases are major resources for gathering data to train these algorithms. While these ...