Now showing items 1-10 of 161
ESTABLISHMENT OF SPERMATOGENESIS FOLLOWING TESTICULAR TISSUE ECTOPIC XENOGRAFTING IN ALPACA
Sperm production depends on development, puberty and germ cell differentiation. Puberty age of alpaca varies and little is known of factors regulating this process. The species is also known for a high incidence of congenital ...
Immunogenicity and Linked Recognition of
Like several other bacterial pathogens,
Role of the N-terminal region of troponin T in cardiac muscle contractile activation
Cardiac muscle contraction is the result of coordinated interactions between the contractile regulatory proteins of the thick and thin filaments, and a detailed understanding of how they interact is central to advancing ...
Insights into the Maternal Age Effect on Aneuploidy
Humans face extraordinary difficulties in reproduction, as over 10% of all pregnancies are aneuploid. In most cases, aneuploidy causes complications in development; indeed, it is the leading known cause of miscarriage and ...
Characterization of Cobalamin-Dependent Radical S-Adenosyl-L-Methionine Methyltransferases Involved in Antibiotic Biosynthesis
Due to increasing antibiotic resistance among dangerous pathogens, there is a critical need for new antibiotics. Enzymes represent a powerful tool for antibiotic production and discovery, however more enzymatic mechanisms ...
CHANNELING SATIATION AT THE ST-NTS SYNAPSE: THE ROLES OF TRP CHANNELS
Vagal afferent neurons relay meal-related signals from the gut to the hindbrain nucleus of the solitary tract (NTS) providing key controls of feeding and gastrointestinal reflexes. Centrally, vagal afferents form strong ...
IDENTIFICATION AND ANALYSIS OF REGULATORY AND SEXUAL STAGE GENES IN THE GENOMES OF BABESIA AND THEILERIA PARASITES
The tick borne apicomplexan parasites Babesia and Theileria are responsible for costly and devastating diseases globally. Improved control is needed but the biology of these parasites remains poorly understood. Significant ...
To Be, or Not to Be: The Molecular Mechanisms that Regulate Spermatogonial Stem Cell Fate
Spermatogonial stem cells (SSCs) are a rare population of cells in the male germ line that self-renew and differentiate into progenitor spermatogonia for the initiation of spermatogenesis. In mammalian males, this process ...
Protective effects of an experimental sporozoite-based immunization strategy against Theileria equi
Theileria equi is a tick-transmitted apicomplexan hemoparasite parasite of equids with a worldwide distribution and a cause of equine piroplasmosis, a World Organization of Animal Health (OIE) reportable disease. Although ...